{"id":4027,"date":"2025-08-30T15:28:24","date_gmt":"2025-08-30T11:58:24","guid":{"rendered":"https:\/\/gimed.ir\/Liver-cancer\/?p=4027"},"modified":"2025-08-30T15:38:31","modified_gmt":"2025-08-30T12:08:31","slug":"management-of-advanced-hcc","status":"publish","type":"post","link":"https:\/\/gimed.ir\/Liver-cancer\/management-of-advanced-hcc\/","title":{"rendered":"Management of advanced HCC"},"content":{"rendered":"\t\t<div data-elementor-type=\"wp-post\" data-elementor-id=\"4027\" class=\"elementor elementor-4027\" data-elementor-post-type=\"post\">\n\t\t\t\t<div class=\"elementor-element elementor-element-f22b753 e-flex e-con-boxed e-con e-parent\" data-id=\"f22b753\" data-element_type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-41b1be7 e-flex e-con-boxed e-con e-parent\" data-id=\"41b1be7\" data-element_type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t<div 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\\u0627\\u0648\\u0644:&lt;\\\/li&gt;&lt;li&gt;&lt;b&gt;Lenvatinib&lt;\\\/b&gt;&lt;\\\/li&gt;&lt;li&gt;&lt;b&gt;Sorafenib&lt;\\\/b&gt;&lt;\\\/li&gt;&lt;\\\/ul&gt;&lt;\\\/li&gt;&lt;\\\/ul&gt;&quot;,&quot;hotspot_offset_x&quot;:{&quot;unit&quot;:&quot;%&quot;,&quot;size&quot;:39,&quot;sizes&quot;:[]},&quot;hotspot_offset_y&quot;:{&quot;unit&quot;:&quot;%&quot;,&quot;size&quot;:31,&quot;sizes&quot;:[]},&quot;hotspot_tooltip_position&quot;:&quot;yes&quot;,&quot;hotspot_position&quot;:&quot;top&quot;,&quot;hotspot_tooltip_width&quot;:{&quot;unit&quot;:&quot;px&quot;,&quot;size&quot;:456,&quot;sizes&quot;:[]},&quot;hotspot_tooltip_text_wrap&quot;:&quot;yes&quot;,&quot;_id&quot;:&quot;0190d61&quot;,&quot;hotspot_position_mobile&quot;:&quot;right&quot;,&quot;hotspot_label&quot;:&quot;&quot;,&quot;hotspot_link&quot;:{&quot;url&quot;:&quot;&quot;,&quot;is_external&quot;:&quot;&quot;,&quot;nofollow&quot;:&quot;&quot;,&quot;custom_attributes&quot;:&quot;&quot;},&quot;hotspot_horizontal&quot;:&quot;right&quot;,&quot;hotspot_vertical&quot;:&quot;top&quot;},{&quot;hotspot_icon&quot;:{&quot;value&quot;:&quot;fas 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data-widget_type=\"hotspot.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<img fetchpriority=\"high\" decoding=\"async\" width=\"800\" height=\"566\" src=\"https:\/\/gimed.ir\/Liver-cancer\/wp-content\/uploads\/2025\/08\/Picture2.png\" class=\"attachment-large size-large wp-image-3993\" alt=\"\" srcset=\"https:\/\/gimed.ir\/Liver-cancer\/wp-content\/uploads\/2025\/08\/Picture2.png 943w, https:\/\/gimed.ir\/Liver-cancer\/wp-content\/uploads\/2025\/08\/Picture2-500x354.png 500w, https:\/\/gimed.ir\/Liver-cancer\/wp-content\/uploads\/2025\/08\/Picture2-300x212.png 300w, https:\/\/gimed.ir\/Liver-cancer\/wp-content\/uploads\/2025\/08\/Picture2-768x543.png 768w\" sizes=\"(max-width: 800px) 100vw, 800px\" \/>\n\t\t\t\t\t\t<div class=\"e-hotspot elementor-repeater-item-6490865  e-hotspot--position-right e-hotspot--position-top   e-hotspot--icon\">\n\n\t\t\t\t\t\t\t\t<div class=\"e-hotspot__button e-hotspot--soft-beat\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"e-hotspot__icon\"><svg class=\"e-font-icon-svg e-fas-info-circle\" viewBox=\"0 0 512 512\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\"><path d=\"M256 8C119.043 8 8 119.083 8 256c0 136.997 111.043 248 248 248s248-111.003 248-248C504 119.083 392.957 8 256 8zm0 110c23.196 0 42 18.804 42 42s-18.804 42-42 42-42-18.804-42-42 18.804-42 42-42zm56 254c0 6.627-5.373 12-12 12h-88c-6.627 0-12-5.373-12-12v-24c0-6.627 5.373-12 12-12h12v-64h-12c-6.627 0-12-5.373-12-12v-24c0-6.627 5.373-12 12-12h64c6.627 0 12 5.373 12 12v100h12c6.627 0 12 5.373 12 12v24z\"><\/path><\/svg><\/div>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"e-hotspot__tooltip  e-hotspot--tooltip-position e-hotspot--fade-in-out \" >\n\t\t\t\t\t\t<p><b>\u0627\u0644\u06af\u0648\u0631\u06cc\u062a\u0645 \u062f\u0631\u0645\u0627\u0646 \u0633\u06cc\u0633\u062a\u0645\u06cc\u06a9 \u0633\u0631\u0637\u0627\u0646 \u06a9\u0628\u062f \u067e\u06cc\u0634\u0631\u0641\u062a\u0647 (<\/b><b>Advanced HCC<\/b><b>)<\/b><\/p>\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t\t\n\t\t\t<\/div>\n\n\t\n\t\t\t\t\t\t<div class=\"e-hotspot elementor-repeater-item-168dd16  e-hotspot--position-right e-hotspot--position-top   e-hotspot--icon\">\n\n\t\t\t\t\t\t\t\t<div class=\"e-hotspot__button e-hotspot--soft-beat\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"e-hotspot__icon\"><svg class=\"e-font-icon-svg e-fas-info-circle\" viewBox=\"0 0 512 512\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\"><path d=\"M256 8C119.043 8 8 119.083 8 256c0 136.997 111.043 248 248 248s248-111.003 248-248C504 119.083 392.957 8 256 8zm0 110c23.196 0 42 18.804 42 42s-18.804 42-42 42-42-18.804-42-42 18.804-42 42-42zm56 254c0 6.627-5.373 12-12 12h-88c-6.627 0-12-5.373-12-12v-24c0-6.627 5.373-12 12-12h12v-64h-12c-6.627 0-12-5.373-12-12v-24c0-6.627 5.373-12 12-12h64c6.627 0 12 5.373 12 12v100h12c6.627 0 12 5.373 12 12v24z\"><\/path><\/svg><\/div>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"e-hotspot__tooltip  e-hotspot--tooltip-position e-hotspot--fade-in-out \" >\n\t\t\t\t\t\t<p><b>. \u0645\u0631\u062d\u0644\u0647 <\/b><b>BCLC B\u2013C<\/b><\/p><p>(\u0628\u06cc\u0645\u0627\u0631\u0627\u0646 \u0645\u0631\u0627\u062d\u0644 \u067e\u06cc\u0634\u0631\u0641\u062a\u0647 \u06a9\u0647 \u0646\u06cc\u0627\u0632\u0645\u0646\u062f \u062f\u0631\u0645\u0627\u0646 \u062f\u0627\u0631\u0648\u06cc\u06cc \u0633\u06cc\u0633\u062a\u0645\u06cc\u06a9 \u0647\u0633\u062a\u0646\u062f)<\/p><p><b>\u0627\u0644\u0641) \u0627\u06af\u0631 \u0628\u06cc\u0645\u0627\u0631 \u0645\u0646\u0627\u0633\u0628 \u0628\u0631\u0627\u06cc \u062f\u0631\u0645\u0627\u0646 \u0628\u0627 \u062f\u0627\u0631\u0648\u0647\u0627\u06cc \u0627\u06cc\u0645\u0646\u06cc\u200c\u062f\u0631\u0645\u0627\u0646\u06cc (<\/b><b>ICI therapy<\/b><b>)<\/b> <b>\u0628\u0627\u0634\u062f:<\/b><\/p><ul><li>\u06af\u0632\u06cc\u0646\u0647\u200c\u0647\u0627\u06cc \u062e\u0637 \u0627\u0648\u0644:<\/li><li><b>Atezolizumab<\/b><b> + Bevacizumab<\/b><\/li><li><b>Durvalumab<\/b><b> + <\/b><b>Tremelimumab<\/b><\/li><li><b>Camrelizumab<\/b><b> + <\/b><b>Rivoceranib<\/b><\/li><li><b>Nivolumab + Ipilimumab<\/b><\/li><li><b>Durvalumab<\/b> <b>\u062a\u06a9\u200c\u062f\u0627\u0631\u0648\u06cc\u06cc<\/b><\/li><\/ul><p><b>Tislelizumab<\/b> <b>\u062a\u06a9\u200c\u062f\u0627\u0631\u0648\u06cc\u06cc<\/b><\/p>\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t\t\n\t\t\t<\/div>\n\n\t\n\t\t\t\t\t\t<div class=\"e-hotspot elementor-repeater-item-d52dce7  e-hotspot--position-right e-hotspot--position-top   e-hotspot--icon\">\n\n\t\t\t\t\t\t\t\t<div class=\"e-hotspot__button e-hotspot--soft-beat\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"e-hotspot__icon\"><svg class=\"e-font-icon-svg e-fas-info-circle\" viewBox=\"0 0 512 512\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\"><path d=\"M256 8C119.043 8 8 119.083 8 256c0 136.997 111.043 248 248 248s248-111.003 248-248C504 119.083 392.957 8 256 8zm0 110c23.196 0 42 18.804 42 42s-18.804 42-42 42-42-18.804-42-42 18.804-42 42-42zm56 254c0 6.627-5.373 12-12 12h-88c-6.627 0-12-5.373-12-12v-24c0-6.627 5.373-12 12-12h12v-64h-12c-6.627 0-12-5.373-12-12v-24c0-6.627 5.373-12 12-12h64c6.627 0 12 5.373 12 12v100h12c6.627 0 12 5.373 12 12v24z\"><\/path><\/svg><\/div>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"e-hotspot__tooltip  e-hotspot--tooltip-position e-hotspot--fade-in-out \" >\n\t\t\t\t\t\t<p><strong>\u067e\u0633 \u0627\u0632 \u0622\u0646 (\u062e\u0637 \u062f\u0648\u0645 \u062f\u0631\u0645\u0627\u0646):<\/strong><\/p><ul><li><b>Lenvatinib<\/b><\/li><li><b>Regorafenib<\/b><\/li><li><b>Cabozantinib<\/b><\/li><li><b>Sorafenib<\/b><\/li><li><b>Ramucirumab<\/b> (\u0628\u0631\u0627\u06cc \u0628\u06cc\u0645\u0627\u0631\u0627\u0646 \u0628\u0627 AFP \u2265 400 \u0646\u0627\u0646\u0648\u06af\u0631\u0645\/\u0645\u06cc\u0644\u06cc\u200c\u0644\u06cc\u062a\u0631)<\/li><\/ul>\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t\t\n\t\t\t<\/div>\n\n\t\n\t\t\t\t\t\t<div class=\"e-hotspot elementor-repeater-item-0190d61  e-hotspot--position-right e-hotspot--position-top   e-hotspot--icon\">\n\n\t\t\t\t\t\t\t\t<div class=\"e-hotspot__button e-hotspot--soft-beat\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"e-hotspot__icon\"><svg class=\"e-font-icon-svg e-fas-info-circle\" viewBox=\"0 0 512 512\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\"><path d=\"M256 8C119.043 8 8 119.083 8 256c0 136.997 111.043 248 248 248s248-111.003 248-248C504 119.083 392.957 8 256 8zm0 110c23.196 0 42 18.804 42 42s-18.804 42-42 42-42-18.804-42-42 18.804-42 42-42zm56 254c0 6.627-5.373 12-12 12h-88c-6.627 0-12-5.373-12-12v-24c0-6.627 5.373-12 12-12h12v-64h-12c-6.627 0-12-5.373-12-12v-24c0-6.627 5.373-12 12-12h64c6.627 0 12 5.373 12 12v100h12c6.627 0 12 5.373 12 12v24z\"><\/path><\/svg><\/div>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"e-hotspot__tooltip  e-hotspot--tooltip-position e-hotspot--fade-in-out \" >\n\t\t\t\t\t\t<p><b>\u0627\u06af\u0631 \u0628\u06cc\u0645\u0627\u0631 \u0645\u0646\u0627\u0633\u0628 \u0628\u0631\u0627\u06cc \u0627\u06cc\u0645\u0646\u06cc\u200c\u062f\u0631\u0645\u0627\u0646\u06cc (<\/b><b>ICI<\/b><b>)<\/b> <b>\u0646\u0628\u0627\u0634\u062f:<\/b><\/p><ul><li style=\"list-style-type: none;\"><ul><li>\u062f\u0631\u0645\u0627\u0646 \u062e\u0637 \u0627\u0648\u0644:<\/li><li><b>Lenvatinib<\/b><\/li><li><b>Sorafenib<\/b><\/li><\/ul><\/li><\/ul>\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t\t\n\t\t\t<\/div>\n\n\t\n\t\t\t\t\t\t<div class=\"e-hotspot elementor-repeater-item-1ab77e3  e-hotspot--position-right e-hotspot--position-top   e-hotspot--icon\">\n\n\t\t\t\t\t\t\t\t<div class=\"e-hotspot__button e-hotspot--soft-beat\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"e-hotspot__icon\"><svg class=\"e-font-icon-svg e-fas-info-circle\" viewBox=\"0 0 512 512\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\"><path d=\"M256 8C119.043 8 8 119.083 8 256c0 136.997 111.043 248 248 248s248-111.003 248-248C504 119.083 392.957 8 256 8zm0 110c23.196 0 42 18.804 42 42s-18.804 42-42 42-42-18.804-42-42 18.804-42 42-42zm56 254c0 6.627-5.373 12-12 12h-88c-6.627 0-12-5.373-12-12v-24c0-6.627 5.373-12 12-12h12v-64h-12c-6.627 0-12-5.373-12-12v-24c0-6.627 5.373-12 12-12h64c6.627 0 12 5.373 12 12v100h12c6.627 0 12 5.373 12 12v24z\"><\/path><\/svg><\/div>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"e-hotspot__tooltip  e-hotspot--tooltip-position e-hotspot--fade-in-out \" >\n\t\t\t\t\t\t<ul><li>\u067e\u0633 \u0627\u0632 \u062e\u0637 \u0627\u0648\u0644 (\u062f\u0631\u0645\u0627\u0646 \u062c\u0627\u06cc\u06af\u0632\u06cc\u0646):<\/li><li>\u0627\u06af\u0631 \u062e\u0637 \u0627\u0648\u0644 <b>Lenvatinib<\/b> \u0628\u0627\u0634\u062f:<\/li><\/ul><p>\u06af\u0632\u06cc\u0646\u0647\u200c\u0647\u0627\u06cc \u0628\u0639\u062f\u06cc:<\/p><ul><li><b>Sorafenib<\/b><\/li><li><b>Regorafenib<\/b><\/li><li><b>Cabozantinib<\/b><\/li><li><b>Ramucirumab<\/b> (\u062f\u0631 AFP \u0628\u0627\u0644\u0627)<\/li><\/ul>\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t\t\n\t\t\t<\/div>\n\n\t\n\t\t\t\t\t\t<div class=\"e-hotspot elementor-repeater-item-643d0cf  e-hotspot--position-right e-hotspot--position-top   e-hotspot--icon\">\n\n\t\t\t\t\t\t\t\t<div class=\"e-hotspot__button e-hotspot--soft-beat\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"e-hotspot__icon\"><svg class=\"e-font-icon-svg e-fas-info-circle\" viewBox=\"0 0 512 512\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\"><path d=\"M256 8C119.043 8 8 119.083 8 256c0 136.997 111.043 248 248 248s248-111.003 248-248C504 119.083 392.957 8 256 8zm0 110c23.196 0 42 18.804 42 42s-18.804 42-42 42-42-18.804-42-42 18.804-42 42-42zm56 254c0 6.627-5.373 12-12 12h-88c-6.627 0-12-5.373-12-12v-24c0-6.627 5.373-12 12-12h12v-64h-12c-6.627 0-12-5.373-12-12v-24c0-6.627 5.373-12 12-12h64c6.627 0 12 5.373 12 12v100h12c6.627 0 12 5.373 12 12v24z\"><\/path><\/svg><\/div>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"e-hotspot__tooltip  e-hotspot--tooltip-position e-hotspot--fade-in-out \" >\n\t\t\t\t\t\t<ul><li>\u0627\u06af\u0631 \u062e\u0637 \u0627\u0648\u0644 <b>Sorafenib<\/b> \u0628\u0627\u0634\u062f:<\/li><li>\u06af\u0632\u06cc\u0646\u0647\u200c\u0647\u0627\u06cc \u0628\u0639\u062f\u06cc:<\/li><li><b>Regorafenib<\/b><\/li><li><b>Cabozantinib<\/b><\/li><li><b>Ramucirumab<\/b> (\u062f\u0631 AFP \u0628\u0627\u0644\u0627)<\/li><\/ul>\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t\t\n\t\t\t<\/div>\n\n\t\n\t\t\t\t\t\t<div class=\"e-hotspot elementor-repeater-item-d3ed36e  e-hotspot--position-right e-hotspot--position-top   e-hotspot--icon\">\n\n\t\t\t\t\t\t\t\t<div class=\"e-hotspot__button e-hotspot--soft-beat\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"e-hotspot__icon\"><svg class=\"e-font-icon-svg e-fas-info-circle\" viewBox=\"0 0 512 512\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\"><path d=\"M256 8C119.043 8 8 119.083 8 256c0 136.997 111.043 248 248 248s248-111.003 248-248C504 119.083 392.957 8 256 8zm0 110c23.196 0 42 18.804 42 42s-18.804 42-42 42-42-18.804-42-42 18.804-42 42-42zm56 254c0 6.627-5.373 12-12 12h-88c-6.627 0-12-5.373-12-12v-24c0-6.627 5.373-12 12-12h12v-64h-12c-6.627 0-12-5.373-12-12v-24c0-6.627 5.373-12 12-12h64c6.627 0 12 5.373 12 12v100h12c6.627 0 12 5.373 12 12v24z\"><\/path><\/svg><\/div>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"e-hotspot__tooltip  e-hotspot--tooltip-position e-hotspot--fade-in-out \" >\n\t\t\t\t\t\t<p><b>\u0645\u0631\u062d\u0644\u0647 <\/b><b>BCLC D<\/b><\/p><p>(\u0628\u06cc\u0645\u0627\u0631\u0627\u0646 \u062f\u0631 \u0645\u0631\u062d\u0644\u0647 \u0627\u0646\u062a\u0647\u0627\u06cc\u06cc \u0628\u06cc\u0645\u0627\u0631\u06cc)<\/p><ul><li>\u062f\u0631\u0645\u0627\u0646: <b>\u0645\u0631\u0627\u0642\u0628\u062a \u062d\u0645\u0627\u06cc\u062a\u06cc (<\/b><b>BSC<\/b><b>)<\/b><\/li><li>\u0634\u0627\u0645\u0644 \u0645\u062f\u06cc\u0631\u06cc\u062a \u062f\u0631\u062f (\u0645\u0627\u0646\u0646\u062f \u0627\u0633\u062a\u0641\u0627\u062f\u0647 \u0627\u0632 <b>SBRT<\/b>)<\/li><\/ul>\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t\t\n\t\t\t<\/div>\n\n\t\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-d9d5dec e-con-full e-flex e-con e-child\" data-id=\"d9d5dec\" data-element_type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-fc0566a elementor-widget elementor-widget-spacer\" data-id=\"fc0566a\" data-element_type=\"widget\" data-widget_type=\"spacer.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<div class=\"elementor-spacer\">\n\t\t\t<div class=\"elementor-spacer-inner\"><\/div>\n\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-0c50772 e-flex e-con-boxed e-con e-parent\" data-id=\"0c50772\" data-element_type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t<div class=\"elementor-element elementor-element-0b7de51 e-con-full e-flex e-con e-child\" data-id=\"0b7de51\" data-element_type=\"container\">\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-0378240 e-con-full e-flex e-con e-child\" data-id=\"0378240\" data-element_type=\"container\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t\t\t<div class=\"elementor-element elementor-element-05cc361 elementor-widget elementor-widget-text-editor\" data-id=\"05cc361\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p><b>\u0646\u06a9\u0627\u062a \u0645\u0647\u0645<\/b><\/p><ul><li>\u0627\u0646\u062a\u062e\u0627\u0628 \u062f\u0631\u0645\u0627\u0646 \u0628\u0633\u062a\u06af\u06cc \u0628\u0647 \u0648\u0636\u0639\u06cc\u062a \u0639\u0645\u0648\u0645\u06cc \u0628\u06cc\u0645\u0627\u0631 (Performance status)\u060c \u0639\u0645\u0644\u06a9\u0631\u062f \u06a9\u0628\u062f (Child\u2013Pugh)\u060c \u0648 \u062f\u0633\u062a\u0631\u0633\u06cc \u0628\u0647 \u062f\u0627\u0631\u0648\u0647\u0627 \u062f\u0627\u0631\u062f.<\/li><li>\u0628\u0631\u062e\u06cc \u062f\u0627\u0631\u0648\u0647\u0627 \u062a\u0646\u0647\u0627 \u062f\u0631 FDA \u06cc\u0627 EMA \u062a\u0623\u06cc\u06cc\u062f \u0634\u062f\u0647\u200c\u0627\u0646\u062f.<\/li><li><b> Ramucirumab<\/b> \u0641\u0642\u0637 \u0628\u0631\u0627\u06cc \u0628\u06cc\u0645\u0627\u0631\u0627\u0646 \u0628\u0627 AFP \u0628\u0627\u0644\u0627 \u06a9\u0627\u0631\u0628\u0631\u062f \u062f\u0627\u0631\u062f.<\/li><li><b>Regorafenib<\/b> <b>\u0648 <\/b><b>Cabozantinib<\/b> \u0628\u06cc\u0634\u062a\u0631 \u0628\u0647\u200c\u0639\u0646\u0648\u0627\u0646 \u062e\u0637 \u062f\u0648\u0645 \u06cc\u0627 \u0633\u0648\u0645 \u0627\u0633\u062a\u0641\u0627\u062f\u0647 \u0645\u06cc\u200c\u0634\u0648\u0646\u062f.<\/li><\/ul>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-9a41433 e-con-full e-flex e-con e-child\" data-id=\"9a41433\" data-element_type=\"container\">\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t","protected":false},"excerpt":{"rendered":"<p>\u0627\u0644\u06af\u0648\u0631\u06cc\u062a\u0645 \u062f\u0631\u0645\u0627\u0646 \u0633\u06cc\u0633\u062a\u0645\u06cc\u06a9 \u0633\u0631\u0637\u0627\u0646 \u06a9\u0628\u062f \u067e\u06cc\u0634\u0631\u0641\u062a\u0647 (Advanced HCC) . \u0645\u0631\u062d\u0644\u0647 BCLC B\u2013C (\u0628\u06cc\u0645\u0627\u0631\u0627\u0646 \u0645\u0631\u0627\u062d\u0644 \u067e\u06cc\u0634\u0631\u0641\u062a\u0647 \u06a9\u0647 \u0646\u06cc\u0627\u0632\u0645\u0646\u062f \u062f\u0631\u0645\u0627\u0646 \u062f\u0627\u0631\u0648\u06cc\u06cc \u0633\u06cc\u0633\u062a\u0645\u06cc\u06a9 \u0647\u0633\u062a\u0646\u062f) \u0627\u0644\u0641) \u0627\u06af\u0631 \u0628\u06cc\u0645\u0627\u0631 \u0645\u0646\u0627\u0633\u0628 \u0628\u0631\u0627\u06cc \u062f\u0631\u0645\u0627\u0646 \u0628\u0627 \u062f\u0627\u0631\u0648\u0647\u0627\u06cc \u0627\u06cc\u0645\u0646\u06cc\u200c\u062f\u0631\u0645\u0627\u0646\u06cc (ICI therapy) \u0628\u0627\u0634\u062f: \u06af\u0632\u06cc\u0646\u0647\u200c\u0647\u0627\u06cc \u062e\u0637 \u0627\u0648\u0644: Atezolizumab + Bevacizumab Durvalumab + Tremelimumab Camrelizumab + Rivoceranib Nivolumab + Ipilimumab Durvalumab \u062a\u06a9\u200c\u062f\u0627\u0631\u0648\u06cc\u06cc Tislelizumab \u062a\u06a9\u200c\u062f\u0627\u0631\u0648\u06cc\u06cc \u067e\u0633 \u0627\u0632 \u0622\u0646 [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[],"tags":[],"class_list":["post-4027","post","type-post","status-publish","format-standard","hentry"],"_links":{"self":[{"href":"https:\/\/gimed.ir\/Liver-cancer\/wp-json\/wp\/v2\/posts\/4027","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/gimed.ir\/Liver-cancer\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/gimed.ir\/Liver-cancer\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/gimed.ir\/Liver-cancer\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/gimed.ir\/Liver-cancer\/wp-json\/wp\/v2\/comments?post=4027"}],"version-history":[{"count":4,"href":"https:\/\/gimed.ir\/Liver-cancer\/wp-json\/wp\/v2\/posts\/4027\/revisions"}],"predecessor-version":[{"id":4037,"href":"https:\/\/gimed.ir\/Liver-cancer\/wp-json\/wp\/v2\/posts\/4027\/revisions\/4037"}],"wp:attachment":[{"href":"https:\/\/gimed.ir\/Liver-cancer\/wp-json\/wp\/v2\/media?parent=4027"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/gimed.ir\/Liver-cancer\/wp-json\/wp\/v2\/categories?post=4027"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/gimed.ir\/Liver-cancer\/wp-json\/wp\/v2\/tags?post=4027"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}