{"id":4011,"date":"2025-08-30T15:01:09","date_gmt":"2025-08-30T11:31:09","guid":{"rendered":"https:\/\/gimed.ir\/Liver-cancer\/?p=4011"},"modified":"2025-08-30T15:07:10","modified_gmt":"2025-08-30T11:37:10","slug":"diagnosis-pathology-and-molecular-biology-in-hcc","status":"publish","type":"post","link":"https:\/\/gimed.ir\/Liver-cancer\/diagnosis-pathology-and-molecular-biology-in-hcc\/","title":{"rendered":"Diagnosis, pathology, and molecular biology in HCC"},"content":{"rendered":"\t\t
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\u062a\u0634\u062e\u06cc\u0635 (<\/b>Diagnosis<\/b>)<\/b><\/p>

  • \u0627\u0631\u0632\u06cc\u0627\u0628\u06cc \u062a\u0634\u062e\u06cc\u0635\u06cc HCC \u0628\u0627\u06cc\u062f \u0634\u0627\u0645\u0644 \u0645\u0648\u0627\u0631\u062f \u0632\u06cc\u0631 \u0628\u0627\u0634\u062f [III, A]:<\/li>
  • \u0634\u0631\u062d\u200c\u062d\u0627\u0644<\/li>
  • \u0645\u0639\u0627\u06cc\u0646\u0647 \u0628\u0627\u0644\u06cc\u0646\u06cc<\/li>
  • \u0622\u0632\u0645\u0627\u06cc\u0634\u200c\u0647\u0627\u06cc \u0622\u0632\u0645\u0627\u06cc\u0634\u06af\u0627\u0647\u06cc<\/li>
  • \u062a\u0635\u0648\u06cc\u0631\u0628\u0631\u062f\u0627\u0631\u06cc<\/li>
  • \u0628\u06cc\u0648\u067e\u0633\u06cc \u062a\u0648\u0645\u0648\u0631<\/li><\/ul>

    \u062a\u0634\u062e\u06cc\u0635<\/strong> HCC<\/strong> \u0628\u0627\u06cc\u062f \u0628\u0631 \u0627\u0633\u0627\u0633 \u0622\u0632\u0645\u0627\u06cc\u0634 \u0628\u0627\u0641\u062a\u200c\u0634\u0646\u0627\u0633\u06cc (\u0647\u06cc\u0633\u062a\u0648\u0644\u0648\u0698\u06cc) \u0648\/\u06cc\u0627 \u06cc\u0627\u0641\u062a\u0647\u200c\u0647\u0627\u06cc \u062a\u0635\u0648\u06cc\u0631\u0628\u0631\u062f\u0627\u0631\u06cc \u0628\u0627 \u06a9\u0646\u062a\u0631\u0627\u0633\u062a \u0627\u0646\u062c\u0627\u0645 \u0634\u0648\u062f [III, A]. \u0628\u0631\u0627\u06cc \u062a\u0634\u062e\u06cc\u0635 \u0628\u0627 \u0633\u06cc\u200c\u062a\u06cc\u200c\u0627\u0633\u06a9\u0646 (CT) \u06cc\u0627 \u0627\u0645\u200c\u0622\u0631\u200c\u0622\u06cc (MRI) \u062f\u0631 \u0628\u06cc\u0645\u0627\u0631\u0627\u0646 \u067e\u0631\u062e\u0637\u0631\u060c \u0645\u06cc\u200c\u062a\u0648\u0627\u0646 \u0648\u06cc\u0698\u06af\u06cc\u200c\u0647\u0627\u06cc \u062a\u0635\u0648\u06cc\u0631\u0628\u0631\u062f\u0627\u0631\u06cc \u0632\u06cc\u0631 \u0631\u0627 \u0628\u0627 \u0647\u0645 \u062a\u0631\u06a9\u06cc\u0628 \u06a9\u0631\u062f [IV, B]:<\/p>

    • \u0627\u0646\u062f\u0627\u0632\u0647 \u062a\u0648\u0645\u0648\u0631<\/li>
    • \u0627\u0641\u0632\u0627\u06cc\u0634 \u062c\u0630\u0628 \u06a9\u0646\u062a\u0631\u0627\u0633\u062a \u062f\u0631 \u0641\u0627\u0632 \u0634\u0631\u06cc\u0627\u0646\u06cc (arterial phase hyperenhancement) \u0628\u062f\u0648\u0646 \u0627\u0644\u06af\u0648\u06cc \u062d\u0644\u0642\u0648\u06cc (non-rim)<\/li>
    • \u0634\u0633\u062a\u0634\u0648\u06cc \u0645\u062d\u06cc\u0637\u06cc (peripheral washout)<\/li>
    • \u0648\u062c\u0648\u062f \u06a9\u067e\u0633\u0648\u0644 \u0642\u0627\u0628\u0644\u200c\u062a\u0634\u062e\u06cc\u0635 (enhancing capsule)<\/li>
    • \u0631\u0634\u062f \u062a\u0648\u0645\u0648\u0631 \u062f\u0631 \u0637\u0648\u0644 \u0632\u0645\u0627\u0646<\/li>
    • \u0628\u0631\u0627\u06cc \u062a\u0634\u062e\u06cc\u0635 \u0628\u0627 \u0627\u0648\u0644\u062a\u0631\u0627\u0633\u0648\u0646\u062f \u06a9\u0646\u062a\u0631\u0627\u0633\u062a\u200c\u062f\u0627\u0631 (CEUS) \u062f\u0631 \u0628\u06cc\u0645\u0627\u0631\u0627\u0646 \u067e\u0631\u062e\u0637\u0631\u060c \u0645\u06cc\u200c\u062a\u0648\u0627\u0646 \u0648\u06cc\u0698\u06af\u06cc\u200c\u0647\u0627\u06cc \u0632\u06cc\u0631 \u0631\u0627 \u062a\u0631\u06a9\u06cc\u0628 \u06a9\u0631\u062f [IV, B]:<\/li>
    • \u0627\u0641\u0632\u0627\u06cc\u0634 \u062c\u0630\u0628 \u06a9\u0646\u062a\u0631\u0627\u0633\u062a \u062f\u0631 \u0641\u0627\u0632 \u0634\u0631\u06cc\u0627\u0646\u06cc (non-rim APHE)<\/li>
    • \u0647\u0645\u0631\u0627\u0647 \u0628\u0627 \u0634\u0633\u062a\u0634\u0648\u06cc \u062f\u06cc\u0631\u0647\u0646\u06af\u0627\u0645 (\u0628\u06cc\u0634 \u0627\u0632 \u06f6\u06f0 \u062b\u0627\u0646\u06cc\u0647) \u0648 \u062e\u0641\u06cc\u0641 (mild washout)<\/li><\/ul>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t
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      <\/path><\/svg><\/div>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\n\t\t\t\t\t\t\t\t\n\t\t\t<\/div>\n\n\t\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t
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      <\/div>\n\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t
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      \u067e\u0627\u062a\u0648\u0644\u0648\u0698\u06cc (<\/b>Pathology<\/b>)<\/b><\/p>

      • \u062f\u0631 \u0628\u06cc\u0645\u0627\u0631\u0627\u0646 \u0628\u062f\u0648\u0646 \u0633\u06cc\u0631\u0648\u0632\u060c \u06cc\u0627 \u062f\u0631 \u0645\u0639\u0631\u0636 \u062e\u0637\u0631 \u067e\u0627\u06cc\u06cc\u0646\u060c \u06cc\u0627 \u0628\u062f\u0648\u0646 \u0641\u0627\u06a9\u062a\u0648\u0631\u0647\u0627\u06cc \u062e\u0637\u0631 \u0634\u0646\u0627\u062e\u062a\u0647\u200c\u0634\u062f\u0647 \u0628\u0631\u0627\u06cc HCC\u060c \u062a\u0623\u06cc\u06cc\u062f \u0647\u06cc\u0633\u062a\u0648\u067e\u0627\u062a\u0648\u0644\u0648\u0698\u06cc\u06a9 (\u0628\u06cc\u0648\u067e\u0633\u06cc \u0627\u0632 \u062a\u0648\u0645\u0648\u0631 \u06a9\u0628\u062f\u06cc \u06cc\u0627 \u0645\u062d\u0644 \u0645\u062a\u0627\u0633\u062a\u0627\u0632 \u062f\u0631 \u0635\u0648\u0631\u062a \u0648\u062c\u0648\u062f) \u0628\u0631\u0627\u06cc \u062a\u0634\u062e\u06cc\u0635 \u062a\u0648\u0635\u06cc\u0647 \u0645\u06cc\u200c\u0634\u0648\u062f [IV, A].<\/li>
      • \u062f\u0631 \u0628\u06cc\u0645\u0627\u0631\u0627\u0646 \u0628\u0627 HCC \u067e\u06cc\u0634\u0631\u0641\u062a\u0647\u060c \u062a\u0634\u062e\u06cc\u0635 \u0647\u06cc\u0633\u062a\u0648\u067e\u0627\u062a\u0648\u0644\u0648\u0698\u06cc\u06a9 \u067e\u06cc\u0634 \u0627\u0632 \u0634\u0631\u0648\u0639 \u062f\u0631\u0645\u0627\u0646 \u0633\u06cc\u0633\u062a\u0645\u06cc\u06a9 \u062a\u0648\u0635\u06cc\u0647 \u0645\u06cc\u200c\u0634\u0648\u062f [III, A].<\/li>
      • \u0628\u0631\u0627\u06cc \u062a\u0648\u0645\u0648\u0631\u0647\u0627\u06cc\u06cc \u06a9\u0647 \u0648\u06cc\u0698\u06af\u06cc\u200c\u0647\u0627\u06cc \u0647\u06cc\u0633\u062a\u0648\u0644\u0648\u0698\u06cc \u062a\u0631\u06a9\u06cc\u0628\u06cc \u062f\u0627\u0631\u0646\u062f\u060c \u0628\u0627\u06cc\u062f \u062a\u0648\u0627\u0644\u06cc\u200c\u06cc\u0627\u0628\u06cc \u0646\u0633\u0644 \u062c\u062f\u06cc\u062f (<\/b>Next-Generation Sequencing \u2013 NGS<\/b>)<\/b> \u0627\u0646\u062c\u0627\u0645 \u0634\u0648\u062f [IV, A].<\/li><\/ul>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t
        \n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t
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        \u0632\u06cc\u0633\u062a\u200c\u0634\u0646\u0627\u0633\u06cc \u0645\u0648\u0644\u06a9\u0648\u0644\u06cc (<\/b>Molecular Biology<\/b>)<\/b><\/p>

        • \u0628\u0647 \u0645\u0646\u0638\u0648\u0631 \u062a\u0633\u0647\u06cc\u0644 \u062a\u0648\u0633\u0639\u0647 \u0628\u06cc\u0648\u0645\u0627\u0631\u06a9\u0631\u0647\u0627\u060c \u0628\u06cc\u0648\u067e\u0633\u06cc \u062a\u0648\u0645\u0648\u0631 \u062f\u0631 \u0647\u0645\u0647 \u0628\u06cc\u0645\u0627\u0631\u0627\u0646\u06cc \u06a9\u0647 \u062f\u0631 \u06a9\u0627\u0631\u0622\u0632\u0645\u0627\u06cc\u06cc\u200c\u0647\u0627\u06cc \u0628\u0627\u0644\u06cc\u0646\u06cc \u0634\u0631\u06a9\u062a \u0645\u06cc\u200c\u06a9\u0646\u0646\u062f \u062a\u0648\u0635\u06cc\u0647 \u0645\u06cc\u200c\u0634\u0648\u062f [IV, A].<\/li>
        • \u062a\u0633\u062a\u200c\u0647\u0627\u06cc \u0698\u0646\u062a\u06cc\u06a9 \u0698\u0631\u0645\u200c\u0644\u0627\u06cc\u0646 (<\/b>germline tests)<\/b> \u0628\u0647\u200c\u0635\u0648\u0631\u062a \u0631\u0648\u062a\u06cc\u0646 \u062f\u0631 \u0632\u0645\u0627\u0646 \u062a\u0634\u062e\u06cc\u0635 \u062a\u0648\u0635\u06cc\u0647 \u0646\u0645\u06cc\u200c\u0634\u0648\u0646\u062f [IV, D]\u060c \u0645\u06af\u0631 \u062f\u0631 \u0645\u0648\u0627\u0631\u062f \u0646\u0627\u062f\u0631 \u0628\u06cc\u0645\u0627\u0631\u06cc\u200c\u0647\u0627\u06cc \u0641\u0627\u0645\u06cc\u0644\u06cc \u0648 \u067e\u0633 \u0627\u0632 \u0645\u0634\u0627\u0648\u0631\u0647 \u0698\u0646\u062a\u06cc\u06a9 [IV, B].<\/li>
        • \u0628\u06cc\u0648\u067e\u0633\u06cc \u0645\u0627\u06cc\u0639 (<\/b>liquid biopsy)<\/b> \u0648 \u062a\u062d\u0644\u06cc\u0644 DNA \u062a\u0648\u0645\u0648\u0631\u06cc \u062f\u0631 \u06af\u0631\u062f\u0634 (<\/b>ctDNA)<\/b> \u0628\u0631\u0627\u06cc \u062a\u0634\u062e\u06cc\u0635 \u0631\u0648\u062a\u06cc\u0646 HCC \u062a\u0648\u0635\u06cc\u0647 \u0646\u0645\u06cc\u200c\u0634\u0648\u0646\u062f [IV, D].<\/li><\/ul>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t
          \n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t","protected":false},"excerpt":{"rendered":"

          \u062a\u0634\u062e\u06cc\u0635 (Diagnosis) \u0627\u0631\u0632\u06cc\u0627\u0628\u06cc \u062a\u0634\u062e\u06cc\u0635\u06cc HCC \u0628\u0627\u06cc\u062f \u0634\u0627\u0645\u0644 \u0645\u0648\u0627\u0631\u062f \u0632\u06cc\u0631 \u0628\u0627\u0634\u062f [III, A]: \u0634\u0631\u062d\u200c\u062d\u0627\u0644 \u0645\u0639\u0627\u06cc\u0646\u0647 \u0628\u0627\u0644\u06cc\u0646\u06cc \u0622\u0632\u0645\u0627\u06cc\u0634\u200c\u0647\u0627\u06cc \u0622\u0632\u0645\u0627\u06cc\u0634\u06af\u0627\u0647\u06cc \u062a\u0635\u0648\u06cc\u0631\u0628\u0631\u062f\u0627\u0631\u06cc \u0628\u06cc\u0648\u067e\u0633\u06cc \u062a\u0648\u0645\u0648\u0631 \u062a\u0634\u062e\u06cc\u0635 HCC \u0628\u0627\u06cc\u062f \u0628\u0631 \u0627\u0633\u0627\u0633 \u0622\u0632\u0645\u0627\u06cc\u0634 \u0628\u0627\u0641\u062a\u200c\u0634\u0646\u0627\u0633\u06cc (\u0647\u06cc\u0633\u062a\u0648\u0644\u0648\u0698\u06cc) \u0648\/\u06cc\u0627 \u06cc\u0627\u0641\u062a\u0647\u200c\u0647\u0627\u06cc \u062a\u0635\u0648\u06cc\u0631\u0628\u0631\u062f\u0627\u0631\u06cc \u0628\u0627 \u06a9\u0646\u062a\u0631\u0627\u0633\u062a \u0627\u0646\u062c\u0627\u0645 \u0634\u0648\u062f [III, A]. \u0628\u0631\u0627\u06cc \u062a\u0634\u062e\u06cc\u0635 \u0628\u0627 \u0633\u06cc\u200c\u062a\u06cc\u200c\u0627\u0633\u06a9\u0646 (CT) \u06cc\u0627 \u0627\u0645\u200c\u0622\u0631\u200c\u0622\u06cc (MRI) \u062f\u0631 \u0628\u06cc\u0645\u0627\u0631\u0627\u0646 \u067e\u0631\u062e\u0637\u0631\u060c \u0645\u06cc\u200c\u062a\u0648\u0627\u0646 \u0648\u06cc\u0698\u06af\u06cc\u200c\u0647\u0627\u06cc \u062a\u0635\u0648\u06cc\u0631\u0628\u0631\u062f\u0627\u0631\u06cc \u0632\u06cc\u0631 \u0631\u0627 \u0628\u0627 \u0647\u0645 […]<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[],"tags":[],"class_list":["post-4011","post","type-post","status-publish","format-standard","hentry"],"_links":{"self":[{"href":"https:\/\/gimed.ir\/Liver-cancer\/wp-json\/wp\/v2\/posts\/4011","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/gimed.ir\/Liver-cancer\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/gimed.ir\/Liver-cancer\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/gimed.ir\/Liver-cancer\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/gimed.ir\/Liver-cancer\/wp-json\/wp\/v2\/comments?post=4011"}],"version-history":[{"count":4,"href":"https:\/\/gimed.ir\/Liver-cancer\/wp-json\/wp\/v2\/posts\/4011\/revisions"}],"predecessor-version":[{"id":4015,"href":"https:\/\/gimed.ir\/Liver-cancer\/wp-json\/wp\/v2\/posts\/4011\/revisions\/4015"}],"wp:attachment":[{"href":"https:\/\/gimed.ir\/Liver-cancer\/wp-json\/wp\/v2\/media?parent=4011"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/gimed.ir\/Liver-cancer\/wp-json\/wp\/v2\/categories?post=4011"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/gimed.ir\/Liver-cancer\/wp-json\/wp\/v2\/tags?post=4011"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}