{"id":4465,"date":"2025-09-01T22:39:34","date_gmt":"2025-09-01T19:09:34","guid":{"rendered":"https:\/\/gimed.ir\/Colorectal-cancer\/?page_id=4465"},"modified":"2025-09-01T22:55:36","modified_gmt":"2025-09-01T19:25:36","slug":"second-line-therapy","status":"publish","type":"page","link":"https:\/\/gimed.ir\/Colorectal-cancer\/second-line-therapy\/","title":{"rendered":"Second-line Therapy"},"content":{"rendered":"\t\t<div data-elementor-type=\"wp-page\" data-elementor-id=\"4465\" class=\"elementor elementor-4465\" data-elementor-post-type=\"page\">\n\t\t\t\t<div class=\"elementor-element elementor-element-bb43ec7 e-flex e-con-boxed e-con e-parent\" data-id=\"bb43ec7\" data-element_type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t<div class=\"elementor-element elementor-element-fa53d73 e-con-full e-flex e-con e-child\" data-id=\"fa53d73\" data-element_type=\"container\">\n\t\t<div class=\"elementor-element elementor-element-1273d61 e-con-full e-flex e-con e-child\" data-id=\"1273d61\" data-element_type=\"container\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;,&quot;background_motion_fx_motion_fx_mouse&quot;:&quot;yes&quot;,&quot;background_motion_fx_mouseTrack_effect&quot;:&quot;yes&quot;,&quot;background_motion_fx_mouseTrack_speed&quot;:{&quot;unit&quot;:&quot;px&quot;,&quot;size&quot;:1,&quot;sizes&quot;:[]}}\">\n\t\t\t\t<div class=\"elementor-element elementor-element-3b50e5a elementor-widget elementor-widget-spacer\" data-id=\"3b50e5a\" data-element_type=\"widget\" data-widget_type=\"spacer.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<div class=\"elementor-spacer\">\n\t\t\t<div class=\"elementor-spacer-inner\"><\/div>\n\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-6999ae8 elementor-widget elementor-widget-heading\" data-id=\"6999ae8\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">Stage IV Unresectable mCRC: Second-line Therapy\n<\/h2>\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-24c0d8e elementor-widget elementor-widget-spacer\" data-id=\"24c0d8e\" data-element_type=\"widget\" data-widget_type=\"spacer.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<div class=\"elementor-spacer\">\n\t\t\t<div class=\"elementor-spacer-inner\"><\/div>\n\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-9a40b5f e-flex e-con-boxed e-con e-parent\" data-id=\"9a40b5f\" data-element_type=\"container\" data-settings=\"{&quot;animation&quot;:&quot;none&quot;}\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t<div class=\"elementor-element elementor-element-b1f3143 e-con-full e-flex elementor-invisible e-con e-child\" data-id=\"b1f3143\" data-element_type=\"container\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;,&quot;animation&quot;:&quot;fadeInLeft&quot;,&quot;animation_delay&quot;:100}\">\n\t\t\t\t<div class=\"elementor-element elementor-element-987027a elementor-widget elementor-widget-spacer\" data-id=\"987027a\" data-element_type=\"widget\" data-widget_type=\"spacer.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<div class=\"elementor-spacer\">\n\t\t\t<div class=\"elementor-spacer-inner\"><\/div>\n\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-c4641bd elementor-widget elementor-widget-heading\" data-id=\"c4641bd\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t<h4 class=\"elementor-heading-title elementor-size-default\"><a href=\"https:\/\/gimed.ir\/Colorectal-cancer\/stage-iv-unresectable-mcrc-other\/\">Stage IV Unresectable mCRC (other)\n<\/a><\/h4>\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-7bd9c04 elementor-widget elementor-widget-spacer\" data-id=\"7bd9c04\" data-element_type=\"widget\" data-widget_type=\"spacer.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<div class=\"elementor-spacer\">\n\t\t\t<div class=\"elementor-spacer-inner\"><\/div>\n\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-4dadc7e elementor-widget elementor-widget-button\" data-id=\"4dadc7e\" data-element_type=\"widget\" data-widget_type=\"button.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<div class=\"elementor-button-wrapper\">\n\t\t\t\t\t<a class=\"elementor-button elementor-button-link elementor-size-sm elementor-animation-push\" href=\"https:\/\/gimed.ir\/Colorectal-cancer\/stage-iv-unresectable-mcrc-other\/\">\n\t\t\t\t\t\t<span class=\"elementor-button-content-wrapper\">\n\t\t\t\t\t\t\t\t\t<span class=\"elementor-button-text\">\u0627\u0637\u0644\u0627\u0639\u0627\u062a \u0628\u06cc\u0634\u062a\u0631 ...<\/span>\n\t\t\t\t\t<\/span>\n\t\t\t\t\t<\/a>\n\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-8b51557 e-con-full e-flex elementor-invisible e-con e-child\" data-id=\"8b51557\" data-element_type=\"container\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;,&quot;animation&quot;:&quot;fadeInLeft&quot;,&quot;animation_delay&quot;:200}\">\n\t\t\t\t<div class=\"elementor-element elementor-element-0c85e19 elementor-widget elementor-widget-spacer\" data-id=\"0c85e19\" data-element_type=\"widget\" data-widget_type=\"spacer.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<div class=\"elementor-spacer\">\n\t\t\t<div class=\"elementor-spacer-inner\"><\/div>\n\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-3673d36 elementor-widget elementor-widget-heading\" data-id=\"3673d36\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t<h4 class=\"elementor-heading-title elementor-size-default\"><a href=\"https:\/\/gimed.ir\/Colorectal-cancer\/ras-wt-and-anti-egfr-naive-braf-mut-dmmr-msi-h-kras-g12c-mut\/\">RAS-wt and anti-EGFR-naive\/BRAF-mut\/dMMR\/MSI-H\/KRAS G12C-mut\n<\/a><\/h4>\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-f3fe819 elementor-widget elementor-widget-spacer\" data-id=\"f3fe819\" data-element_type=\"widget\" data-widget_type=\"spacer.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<div class=\"elementor-spacer\">\n\t\t\t<div class=\"elementor-spacer-inner\"><\/div>\n\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-85e3688 elementor-widget elementor-widget-button\" data-id=\"85e3688\" data-element_type=\"widget\" data-widget_type=\"button.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<div class=\"elementor-button-wrapper\">\n\t\t\t\t\t<a class=\"elementor-button elementor-button-link elementor-size-sm elementor-animation-push\" href=\"https:\/\/gimed.ir\/Colorectal-cancer\/ras-wt-and-anti-egfr-naive-braf-mut-dmmr-msi-h-kras-g12c-mut\/\">\n\t\t\t\t\t\t<span class=\"elementor-button-content-wrapper\">\n\t\t\t\t\t\t\t\t\t<span class=\"elementor-button-text\">\u0627\u0637\u0644\u0627\u0639\u0627\u062a \u0628\u06cc\u0634\u062a\u0631 ...<\/span>\n\t\t\t\t\t<\/span>\n\t\t\t\t\t<\/a>\n\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t","protected":false},"excerpt":{"rendered":"<p>Stage IV Unresectable mCRC: Second-line Therapy Stage IV Unresectable mCRC (other) \u0627\u0637\u0644\u0627\u0639\u0627\u062a \u0628\u06cc\u0634\u062a\u0631 &#8230; RAS-wt and anti-EGFR-naive\/BRAF-mut\/dMMR\/MSI-H\/KRAS G12C-mut \u0627\u0637\u0644\u0627\u0639\u0627\u062a \u0628\u06cc\u0634\u062a\u0631 &#8230;<\/p>\n","protected":false},"author":1,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"footnotes":""},"class_list":["post-4465","page","type-page","status-publish","hentry"],"_links":{"self":[{"href":"https:\/\/gimed.ir\/Colorectal-cancer\/wp-json\/wp\/v2\/pages\/4465","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/gimed.ir\/Colorectal-cancer\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/gimed.ir\/Colorectal-cancer\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/gimed.ir\/Colorectal-cancer\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/gimed.ir\/Colorectal-cancer\/wp-json\/wp\/v2\/comments?post=4465"}],"version-history":[{"count":7,"href":"https:\/\/gimed.ir\/Colorectal-cancer\/wp-json\/wp\/v2\/pages\/4465\/revisions"}],"predecessor-version":[{"id":4484,"href":"https:\/\/gimed.ir\/Colorectal-cancer\/wp-json\/wp\/v2\/pages\/4465\/revisions\/4484"}],"wp:attachment":[{"href":"https:\/\/gimed.ir\/Colorectal-cancer\/wp-json\/wp\/v2\/media?parent=4465"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}